Among a range of pharmaceutical and medical device packaging developments that Klöckner Pentaplast (Montabaur, Germany) will present at ASEAN Pharma Packaging Conference 2017 (APPCON), November 2 – 3, 2017, in Mumbai, India, is a new blister packaging innovation, Pentapharm LiquiGuard. It permits hot- and cold-fill liquids and semi-solids to be formed and packaged directly in a crystal-clear, thermostable laminate film that protects sensitive products from package leaching and moisture gain or loss.
“Pentapharm LiquiGuard provides an advanced option for unit-dose packaging of liquid or semi-solid medications that require resistance to extreme temperatures from hot (120°C/248°F filling) to cold (-183°C/-297°F and lyophilized) during processing, while offering all the benefits of a clear, thermoformable blister film with a customizable moisture barrier,” states Frank Oliveri, Director Global Business Development, Pharmaceutical Packaging.
Daniel Stagnaro, Product Marketing Manager, Barrier Products, explains the distinct technical advantages of the film for PlasticsToday.
“Lower cost versions for food applications of heat resistance products are based on polypropylene or polystyrene,” he says. “The PP version cannot be thermoformed in unsupported web machines without significant shrinkage issues. PS versions present leeching, extractible and organoleptic issues. LiquiGuard is the only product addressing all this issues in a thermoformable substrate.”
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Stagnaro says the materials are presently used in two customer applications, but due to non-disclosure agreement cannot identify either one.
LiquiGuard is currently produced in U.S. “Europe and Asia are capable of production should a market need demand it,” he adds.
The barrier is customizable by the following, according to Stagnaro:
- The moisture barrier can be increased by adjusting the thickness of Aclar (polychlorotrifluoroethylene, PCTFE);
- The oxygen barrier can be adjusted by adding an ethylene vinyl alcohol (EVOH) layer or by replacing Aclar with polyvinylidene chloride (PVdC).
No-barrier versions are also available upon request, Stagnaro says.
“The market values economical solutions as well as performance,” he tells PlasticsToday. “We expect a high level of interest from the scientific point of view and a moderate from the commercial.”